Reversible Fluindione-Induced Chronic Interstitial Nephritis
نویسندگان
چکیده
Fluindione is well known to induce acute drug-induced interstitial nephritis (IN). Most cases occurred soon after the onset of treatment. We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun. Renal function dramatically improved after fluindione withdrawal and steroid therapy.
منابع مشابه
Acute and chronic nephropathy induced by fluindione must be addressed.
BACKGROUND Among the vitamin K antagonists (VKA), indanedione-derived VKA is suspected to induce an immunoallergic risk. One indanedione-derived VKA, fluindione, is still being used in France. The aim of this study was to evaluate the contribution of VKA to acute and chronic nephritis. METHODS Twenty-four cases of biopsy proven acute interstitial nephritis (AIN) were retrospectively selected,...
متن کاملImmuno-allergic interstitial nephritis related to fluindione: first biopsy proven cases.
Case 1. A 72-year-old man was admitted to our unit for acute renal failure (serum creatinine 353 mmol/l vs 107mmol/l at baseline). He had started fluindione for atrial fibrillation five weeks before. Clinical examination was normal. There was no eosinophilia. Urine protein/creatinine ratio was 25mg/mmol, containing low molecular weight protein without albumin. There was no haematuria or pyuria....
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عنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016